To print this page click the PRINT icon on your browser. This page represents a printable version of the following page: http://www.lrf.org.uk/en/1/discaltrials.html Diseases Childhood Acute Lymphoblastic Leukaemia Trials Information Booklet A booklet produced by Leukaemia Research Fund giving background information on clinical trials is available to download. Clinical Trials - PDF Text version of the booklet Registers of Trials Current Controlled Trials International Cancer Research Portfolio - a register of UK and US cancer research (including trials) Last updated 25/11/2008 Leukaemia Research sponsored trials European Intergroup Study on Post Induction Treatment of Philadelphia Positive Acute Lymphoblastic Leukaemia with Imatinib (EsPhALL) Trial Code: UKCRN ID 1425 Type: II/III Status: Open Link: http://clinicaltrials.gov/show/NCT00287105 Website: No website listed Leukaemia Research is funding the UK arm of this trial The Leukaemia Research Fund is funding the MRD-testing element of the UKALL2003 clinical trial. See below for full details of this trial. Last updated 14/11/2008 Non-Leukaemia Research sponsored trials United Kingdom Childhood Acute Lymphoblastic Leukaemia Randomised Trial 2003 (MRC UKALL 2003) Trial Code: 07355119 Type: Phase III Status: Open Link: http://www.controlled-trials.com/mrct/trial/120053... MRD High Risk group randomised to standard vs intensified therapy MRD Low Risk group randomised to standard vs reduced therapy An International Collaborative Trial for Relapsed and Refractory Acute Lymphobalstic Leukaemia (UKALL R3) Trial Code: 07355119 Type: Phase III Status: Open Link: http://www.controlled-trials.com/ISRCTN45724312/Re... To examine the biology of relapsed Acute Lymphoblastic Leukaemia (ALL) and improve its outcome using a combination of chemotherapy and nationally standardised approach to Haematopoietic Stem Cell Transplantation (HSCT). International collaborative treatment protocol for infants under one year with acute lymphoblastic leukaemia Type: Phase III Status: Ongoing Link: http://www.controlled-trials.com/mrct/trial/CHILDH... To improve the outcome for infants (under the age of 1) with acute lymphoblastic leukaemia (ALL) - a group of children with a very poor prognosis who have not so far benefited from the advances in treatment seen in other childhood leukaemias. Last updated 14/11/2008

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