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*The Myelodysplastic Syndromes Trials
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*Information Booklet

A booklet produced by Leukaemia Research Fund giving background information on clinical trials is available to download.
resourceClinical Trials - PDF

Text version of the booklet

*Registers of Trials

Current Controlled Trials
International Cancer Research Portfolio - a register of UK and US cancer research (including trials)

Last updated 14/11/2008

*Leukaemia Research sponsored trials

A randomized trial for patients with acute myeloid leukaemia or high-risk myelodysplastic syndrome aged 60 or over
Trial Code:62207270
Type:Phase III
Status:Open
Link:http://www.controlled-trials.com/mrct/trial/MYELOD...
The aim of this trial is to compare two strategies of treatment for patients with Acute Myeloid Leukaemia or High-Risk Myelodysplastic Syndrome and to compare treatment options within these two strategies. The main objective is to determine whether there are differences in response rates, survival, quality of life and supportive care requirements between the two strategies in patients where there is uncertainty as to the best treatment approach.

WT1 peptide vaccination for leukaemia - a phase I/II pilot study
Type:Phase I/II
Status:Not Stated
The aim of this trial is to use a vaccine that stimulates an immune response against malignant blood cells that display the Wilms tumour antigen-1 (WT1). High levels of WT1 are usually produced by leukaemia cells in patients with acute or chronic myeloid leukaemia and patients with myelodysplastic syndrome (MDS). Although treatments for this group of patients are available, WT1 vaccination may offer a better alternative to the currently available treatments.

Last updated 14/11/2008

*Non-Leukaemia Research sponsored trials

There are no ongoing non-LRF sponsored trials in MDS
Last updated 14/11/2008

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