|  |  |  | | | | Diseases | |  | Essential thrombocythaemia Trials |
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| |  | Information Booklet |
A booklet produced by Leukaemia Research Fund giving background information on clinical trials is available to download.
Text version of the booklet
| Registers of Trials |
Current Controlled Trials
International Cancer Research Portfolio - a register of UK and US cancer research (including trials)
Last updated 14/11/2008
| Leukaemia Research sponsored trials |
There are currently no LRF-supported clinical trials for essential thrombocythaemia.
Last updated 14/11/2008
| Non-Leukaemia Research sponsored trials |
| A Medical Research Council Randomised Trial to Compare Aspirin versus Hydroxyurea/Aspirin in Intermediate Risk Primary Thrombocythaemia and Hydroxyurea/Aspirin versus Anagrelide/Aspirin in High Risk Primary Thrombocythaemia | | Trial Code: | ISRCTN72251782 | | Type: | Phase III | | Status: | Open | | Link: | http://www.controlled-trials.com/mrct/trial/THROMB... | | Website: | http://212.219.75.230/scripts/ukcccr/ibmhpj/bin/DisDetail.exe?MRC%20PT1:0:user:guest | | 1. To assess the incidence of vascular occlusion in low risk patients while receiving aspirin only. 2. To determine whether hydroxyurea reduces vascular occlusive events when added to aspirin in intermediate risk patients. 3. To determine whether anagrelide reduces vascular occlusive events as effectively as hydroxyurea in high risk patients 4. To determine whether anagrelide is as effective as hydroxyurea in reducing elevated platelet counts in high risk patients. 5. To assess the effect of the treatment modalities on quality of life. 6. To assess whether in high and intermediate risk patients treatment modality alters the risk of leukaemia and myelofibrotic transformations. |
Last updated 14/11/2008 |
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